MAYA (smart Mirrors to support healthier lives of Adolescents and Young Adults after cancer) is a four-year project that aims to empower AYA cancer survivors to manage their cardiovascular health and lifestyle with the support of innovative digital tools specifically designed to address cardiotoxic-related late effects of cancer treatment, from the convenience of their homes.
The project’s main objective is to reduce the risk of major cardiac events in AYA cancer survivors by 30-40% by addressing modifiable risk factors such as hypertension, diabetes and obesity, ultimately improving both cardiovascular outcomes and quality of life
Adolescents and Young Adults (AYA) can develop various cancers, often requiring treatments such as chemotherapy, hormone therapy, targeted therapy, immunotherapy, radiation, and surgery.
Common long-term effects of these treatments include:
Late-onset cardiovascular toxicity usually occurs ≥1 year after completion of cancer treatment. It may develop progressively over time or suddenly, triggered by stress or other comorbidities
Late-onset cardiovascular toxicity is common in survivors of childhood, adolescent, and young adult (AYA) cancers, particularly those treated with anthracyclines and/or chest radiation
(≥250–300 mg/m²)
Late-onset cardiovascular toxicities can be subclinical (no symptoms initially) or clinical (with symptoms) and are a leading cause of non-cancer morbidity.
→ Early intervention and lifelong surveillance are crucial in preventing disease progression
MAYA uses AI-driven digital health technologies for personalised and context-aware interactions can effectively prevent, monitor, and manage cardiovascular late effects in AYA cancer survivors.
MAYA employs a combination of real-time biomarker tracking, including physiological and behavioural information, along with insights gathered from survivors themselves through the iCARE health hub equipped with a smart mirror and an AI-powered conversational agent. The iCARE health hub isdesigned to monitor and manage late-onset cardiovascular health issues and address gaps in care during the transition to post-
treatment stages.
Additionally, the iCARE hubs aim to improve health literacy by offering personalised coaching, helping survivors better understand and navigate their health. Installing these tools in homes across different European countries will enable us to evaluate their effectiveness and the acceptance of these innovative technologies
